MacroDose or Trip Tips




☑️ Safer and More Enjoyable Mushroom Usage Checklist


👨‍⚕️ 1. Avoid with certain health conditions

⛑ Helps avoid serious risks.

Avoid psychedelics if:

  • There is a current or past history of schizophrenia or other psychotic disorders, Bipolar I or II disorder.

You should have:

  • Good general health, not pregnant

  • Healthy blood pressure​

💉 2. Avoid drugs that interact with psychedelics

⛑ Helps avoid serious risks.

You should:

  • Not be using tricyclic antidepressants or lithium, SSRIs, haloperidol, or MAOIs

  • Not be using 5-HTP, St John’s Wort or any other supplements that “may affect serotonergic function”

  • Not be using Ritonavir/Indinavir

SSRIs are not reported to cause a dangerous interaction, though they are reported to substantially decrease the effects of shrooms.

Smoking weed while on shrooms? Some users choose to consume cannabis while on shrooms, this is a personal preference and should not be done by those that are not experienced with cannabis already.

⚖️ 3. Use a safe dosage and consider starting with ~0.8 grams of dried mushrooms


Start small

With shrooms, start first with ~0.8 grams.

You may then increase to a maximum of ~1.6 grams, then a maximum of ~3.2 grams, and then a maximum of ~4.8 grams.

Does dosage vary by weight?

It doesn’t seem like dose should vary by weight, at least not much. Though in practice we find that larger bodied people DO need a larger dose to get similar effects.

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🏠 4.Trip in a safe, pleasing and familiar environment

Your environment psychedelic-prep checklist:

  • 🤕 Any potentially dangerous objects should be removed or made safer.

  • 🖼 No windows that could be exited “if in a delusional state”

  • 🏡 You’re very familiar with the environment.

  • Clean your space the night before.

  • Have zero responsibilities on the day of the experience

  • Avoid unpleasant things or people

  • Have Privacy

😄 5. Wait until you’re in a good mindset

Your trip will likely be easier and more enjoyable if you’re in a good mindstate.


📝 6. Prepare yourself

😁 Helps maximize positivity.

You can

  • Buy and read The Psychedelic Explorer’s Guide by Fadiman. If you aren’t convinced, listen to this podcast episode with Fadiman and author Tim Ferriss first.

  • Review the range of experiences that may result from consuming hallucinogens, including changes in perception, sense of time and space, and emotion.

  • Plan how to deal with anxiety or fear​

  • Make a 10 hour music playlist. Some psychedelic music ideas here.

  • Set your intentions, but don’t have expectations​

🎧 7. Optional: Wear eyeshades and headphones

Eyeshades and headphones can make it safer and may contribute to safety by reducing the distractions of environmental stimuli.


🙏 8. Respect psychedelics

Have an appreciation for how powerful the psychological effects of psychedelics can be.


🗓 9. Don’t trip again until you feel your previous trip has been fully integrated into your normal life

😁 Integration involves taking your experience and trying to get positive benefits from it in your daily life.

Make no major decisions for a few days.

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More tips

  • There are some supplements that may help you further reduce the risk of a bad trip. See supplements for psychedelics like LSD and shrooms.

📅 Follow these tips for the day of your trip

  • You should give your phone to the sitter

  • No driving.

  • Treat psychedelics as a two-day experience.

  • Get 8+ hours of sleep the night before and the night after.

  • Make sure you have zero responsibilities for the day and the day after ideally.

  • Eat some light food, perhaps some fruit, citrus helps amplify psychedelics

  • Eat a good and healthy meal 1-2 hrs before you trip

  • Lean into the discomfort. (Alternatively: “Whenever in doubt, turn off your mind, relax, float downstream.”)

What are the best activities for a Shroom trip?

  • For fun and entertainment

  • Enjoying nature

  • Hanging out with friends


  • For significance

  • Introspection

  • Looking at lit candles, “family photographs, a mirror, artistic objects, flowers, and other beautiful natural or manmade objects”